L-theanine: Unlocking Calm and Focus for a Sharper Mind

L-theanine: Unlocking Calm and Focus for a Sharper Mind

Key Takeaways

L-theanine Benefits

1. Neurotransmitters Inducement

L-theanine boosts neurotransmitters like serotonin, dopamine, and GABA, enhancing brain function. It also increases (BDNF) and (NGF), promoting new brain cell growth.

2. Relaxation Brainwaves Stimulation

L-theanine induces relaxation by increasing alpha brainwave activity, promoting a calm state of mind within 30 to 40 minutes.

3. Stress and Anxiety Reduction

L-theanine reduces stress and anxiety by enhancing mental resilience, lowering heart rate, and increasing GABA levels, which promotes relaxation. 

4. Sleep Regulation

L-theanine improves sleep quality without causing drowsiness, making it a valuable sleep aid.

5. Mental Performance Enhancement

L-theanine, in combination with caffeine and EGCG from tea, enhances mental performance by creating a synergistic effect that boosts mood, focus, concentration, and alertness without causing overstimulation or jitters.

6. Neuron Protection

L-theanine has neuroprotective properties, benefiting cognition, memory, and protection against strokes and neurotoxins. It also increases blood flow to the brain, supporting brain health.

What is L-theanine

Let's dive into the fascinating world of L-theanine. L-theanine, also known simply as theanine, is an amino acid that does wonders for our well-being. It has this unique ability to promote a state of calm attentiveness without making you feel drowsy. You can find L-theanine in various teas, such as white, green, oolong, and black. These teas are all made from the leaves of the same evergreen bush called Camilla Sinensis.

Now, here's an interesting tidbit: L-theanine doesn't only exist in tea. It's also in a wild mushroom called Xerocomus badius, which you won't typically find at your local supermarket. This mushroom grows in specific forests in Europe and North America. [1]

While some sources claim that green tea is the ultimate source of L-theanine, that's not entirely accurate. Several studies have shown that L-theanine levels are similar across different teas, including black, green, white, and oolong. [2]

In fact, one study even found that black tea has the highest levels of L-theanine while green tea has the lowest. [3]

But green tea gets most of the attention because that's where L-theanine was initially discovered.

Do you know how tea has this unique umami or savory taste? Well, that's thanks to L-theanine! This compound is responsible for giving tea that special flavor, which happens to be the fifth taste humans can detect.

What makes L-theanine even more incredible is that it easily enters your brain. [4] This makes it an effective ingredient alone and when included in brain supplements.

Mental Benefits of L-theanine

1. L-theanine Boosts Neurotransmitters

One of the coolest things about L-theanine is its direct impact on your brain chemistry. Do you know those little messengers in your brain called neurotransmitters? Well, L-theanine boosts their levels, and these neurotransmitters are crucial for brain cells to communicate with each other.

L-theanine ramps up the levels of some of the most important neurotransmitters, like serotonin, dopamine, and GABA. And guess what? This boost in neurotransmitters has some pretty awesome effects on your brain functions. It helps improve recall, and learning abilities and even boosts our overall mood. It's like a natural brain enhancer! [5]

Here's something interesting: L-theanine also plays a role in the dopamine reward pathway. [6] This means it can actually help people who are trying to quit smoking. By acting on this pathway, L-theanine has shown promising results in assisting smokers on their quitting journey.

Now, get this: even though our bodies don't naturally produce L-theanine, it still acts as a neurotransmitter in the brain. It's like a VIP guest that gets invited to the brain's communication party, even though it didn't grow up there. That's pretty impressive, right?

There's more! L-theanine goes the extra mile by increasing the levels of two other essential brain chemicals: brain-derived neurotrophic factor (BDNF) [7] and nerve growth factor (NGF). [8] These substances are like superheroes that stimulate the growth of new brain cells and neurons. So, thanks to L-theanine, our brains get an extra boost in creating new connections and keeping our gray matter in tip-top shape.

2. L-theanine Induces Brainwaves Associated with Relaxation

Let's talk about brainwaves! It turns out that L-theanine has a pretty fascinating way of bringing about a state of calmness by altering our brain waves!

Your brain cells use electrical signals to communicate with each other. These electrical activities create patterns that we call brain waves. There are five main brainwave patterns, each corresponding to a different state of awareness.

Now, here's where L-theanine comes in. When you take L-theanine, it actually increases alpha activity in your brain. [9] Alpha waves are associated with relaxation and attention. It's like that calm state of mind you reach during meditation. So, by taking a regular dose of L-theanine, you can experience similar benefits to meditation without going full-on cross-legged on a cushion.

And here's the best part: the relaxing effects of L-theanine kick in pretty quickly. Within just 30 to 40 minutes, you should start noticing its calming influence. It's like a fast track to a tranquil state of mind. [10]

3. L-theanine Reduces Stress and Anxiety

L-theanine can be a game-changer when dealing with stress and anxiety.

When you face stress, mentally and physically, L-theanine comes to the rescue. It has this incredible ability to reduce your stress responses, helping you become more mentally resilient. [11] In social situations where anxiety often creeps in, L-theanine can lower those anxious feelings. It's like having a secret weapon against social jitters. [12]

But it doesn't stop there. L-theanine can also have a positive impact on our physiological responses to stress. It can lower your heart rate and help you maintain healthy blood pressure levels in stressful situations. [13]

One of the key ways L-theanine helps alleviate anxiety is by increasing the levels of GABA, a neurotransmitter that plays a vital role in relaxation. When our GABA levels are low, it becomes much harder to quiet our minds, and we may often feel overwhelmed and overstimulated. But with the help of L-theanine, we can boost our GABA and find a sense of calm amidst the chaos.

What's even more impressive is that research has shown L-theanine to be as effective as commonly prescribed anti-anxiety medications. In a study where participants were subjected to artificially induced stress, some were given L-theanine. Others were given Xanax, a popular anti-anxiety medication. Surprisingly, those who received L-theanine had lower baseline anxiety than those who took Xanax. It's a testament to the anxiety-relieving powers of L-theanine. [14]

And here's another interesting finding: when L-theanine is taken alongside antipsychotic medication, it can help reduce anxiety symptoms in individuals with schizophrenia. [15] It's a potential ally in managing anxiety-related challenges in specific mental health conditions.

4. L-theanine Improves Your Sleep Quality

We all know how important it is to catch those Zs, right? Well, L-theanine can lend a helping hand in that department!

Here's the deal: getting high-quality sleep is one of the best things you can do for your brain. During sleep, your brain goes into repair mode, grows new brain cells, and even consolidates all the memories of your day.

What sets L-theanine apart from most natural sleep supplements is that it doesn't actually put you to sleep. Instead, it focuses on making your sleep experience better. How cool is that? It's like having a sleep upgrade!

In fact, a study found that taking L-theanine before bed can improve the quality of your sleep. [16] So, if you've been struggling to get those restful nights, L-theanine might be the missing puzzle piece.

And here's a bonus: unlike pharmaceutical sleeping aids, L-theanine won't leave you feeling drowsy the next day. It's a win-win situation!

5. L-theanine Enhances Mental Performance

Alongside L-theanine, tea contains two other noteworthy compounds: caffeine and EGCG (epigallocatechin gallate). The fascinating thing is that these three compounds work together in harmony when you enjoy a cup of tea. It's like a team effort! [17]

When caffeine and L-theanine team up, something magical happens. They have a synergistic effect that can enhance your performance on mentally demanding tasks even more than caffeine alone. The best part is that this combo won't leave you feeling wired and jittery like caffeine alone might. L-theanine helps balance out and mitigate the overstimulating effects of caffeine. [18]

Because of this unique caffeine-enhancing property, L-theanine has become a popular supplement for those seeking optimal mental performance. Think college students, people in high-pressure jobs, and even biohackers. When combined, L-theanine and caffeine create a powerful nootropic "stack" that boosts mood, focus, concentration, and alertness. [19] And the best part is it's a safe and effective way to maximize mental performance without resorting to drugs.

Let's not forget about EGCG. This compound in tea has its own particular role to play. It helps normalize GABA activity. GABA is a relaxing brain chemical often referred to as "nature's Valium." So, in a way, EGCG helps create a soothing and calming effect in your brain. [20] And just like L-theanine, EGCG also has the ability to alter your brainwave patterns, inducing a relaxed yet attentive state.

So, next time you sip a cup of tea, remember it's not just about L-theanine. It's about the dynamic trio of L-theanine, caffeine, and EGCG working together to boost your mental performance, create a state of calm attentiveness, and help you reach your full potential.

6. L-theanine Protects The Neurons

Let's dive into the neuroprotective powers of L-theanine! This fantastic compound has a calming effect and guards our brain and nervous system. [21]

As we age, it's natural for our cognitive abilities to undergo changes. However, L-theanine steps in to lend a helping hand. Studies conducted in countries where tea is a traditional drink, such as Japan and China, have found that seniors who regularly drink tea perform better in attention, memory, and information-processing tasks than those who don't. [22]

But the benefits of L-theanine don't stop there. It has shown promise in improving cognition and memory, even in individuals diagnosed with mild cognitive impairment (MCI), a type of cognitive decline. [23]

L-theanine also plays a role in protecting our brains from strokes. It can help prevent the death of brain cells following a transient ischemic attack (TIA), a type of stroke. [24]

When it comes to neurotoxins, L-theanine has our back there too. It can protect our brains from environmental neurotoxins that are believed to contribute to conditions like Parkinson's disease. [25]

Another fascinating aspect of L-theanine is its ability to increase blood flow to the brain. This enhanced blood flow nourishes our brain cells, providing them with the oxygen and nutrients they need to thrive. [26]

So, whether it's safeguarding against age-related cognitive decline, protecting against stroke, shielding against neurotoxins, or boosting blood flow, L-theanine has our brain's back.

How to Get the Most L-theanine from Tea

If you're considering getting your L-theanine fix from tea, you might wonder how much tea you should drink. The general recommendation is to aim for around 3 cups of tea daily. It's a nice balance that gives you a good dose of L-theanine without going overboard. Drinking too much tea isn't advised for a few reasons, like consuming excessive caffeine.

When it comes to the type of tea you choose, here's the good news: black, white, oolong, and green teas all contain similar amounts of L-theanine. So, you have some flexibility in selecting your preferred tea variety.

Here's an interesting tip: you can influence the amount of L-theanine in your tea based on how you brew and drink it. The brewing time is the key factor in determining the L-theanine content in your cup of tea. [27] If you want to maximize the L-theanine goodness, always stick to the full steep time recommended. That way, you'll ensure you're getting the most out of your tea.

And here's a little fact: milk may affect the availability of L-theanine in your tea. While a small amount of milk is generally not an issue, a generous splash of milk can significantly reduce the detectable levels of L-theanine in your tea. So, if you're aiming to enjoy the benefits of L-theanine, it might be best to have your tea without a hefty dose of milk.

Remember, moderation is key. Enjoying around 3 cups of tea daily and following proper brewing practices will help you make the most of the L-theanine content in your tea.

Safety and Side Effects

Generally, tea is considered safe with minimal side effects unless you consume too much caffeine. Let's take a closer look at what to watch out for.

Consuming excessive amounts of caffeine can lead to side effects such as anxiety, insomnia, headaches, irregular heartbeat, restlessness, tinnitus (ringing in the ears), and nausea. So, it's essential to be mindful of caffeine intake and not go overboard with tea consumption.

It's worth noting that excessive tea consumption can also interfere with the absorption of iron from food, which can worsen anemia. [28] If you're pregnant or breastfeeding, limit your tea intake to no more than 2 cups per day.


In a world that often feels overwhelming, finding ways to unlock calmness and focus for a sharper mind is invaluable. L-theanine, with its natural and scientifically backed benefits, offers a solution that is both effective and gentle. By incorporating L-theanine into your routine through tea consumption or supplements, you can experience tranquility, enhanced cognitive abilities, and improved overall well-being that it provides. Embrace the power of L-theanine and unlock your true mental potential.

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[1]Production of theanine by Xerocomus badius (mushroom) using submerged fermentation - ScienceDirect

[2]Theanine and Caffeine Content of Infusions Prepared from Commercial Tea Samples - PMC (nih.gov)

[3]How much theanine in a cup of tea? Effects of tea type and method of preparation | Request PDF (researchgate.net)

[4]Effects of theanine, r-glutamylethylamide, on neurotransmitter release and its relationship with glutamic acid neurotransmission - PubMed (nih.gov)

[5]The neuropharmacology of L-theanine(N-ethyl-L-glutamine): a possible neuroprotective and cognitive enhancing agent - PubMed (nih.gov)

[6]L-theanine inhibits nicotine-induced dependence via regulation of the nicotine acetylcholine receptor-dopamine reward pathway - PubMed (nih.gov)

[7]Behavioral and molecular evidence for psychotropic effects in L-theanine - PubMed (nih.gov)

[8]Theanine, r-glutamylethylamide, increases neurotransmission concentrations and neurotrophin mRNA levels in the brain during lactation - PubMed (nih.gov)

[9]L-theanine, a natural constituent in tea, and its effect on mental state - PubMed (nih.gov)

[10]L-theanine, a natural constituent in tea, and its effect on mental state - PubMed (nih.gov)

[11]l-Theanine reduces psychological and physiological stress responses - ScienceDirect

[12]Anti-stress effect of theanine on students during pharmacy practice: positive correlation among salivary α-amylase activity, trait anxiety and subjective stress - PubMed (nih.gov)

[13]Effects of L-theanine or caffeine intake on changes in blood pressure under physical and psychological stresses | Journal of Physiological Anthropology | Full Text (biomedcentral.com)

[14]The acute effects of L-theanine in comparison with alprazolam on anticipatory anxiety in humans - PubMed (nih.gov)

[15]L-theanine relieves positive, activation, and anxiety symptoms in patients with schizophrenia and schizoaffective disorder: an 8-week, randomized, double-blind, placebo-controlled, 2-center study - PubMed (nih.gov)

[16]In Search of a Safe Natural Sleep Aid - PubMed (nih.gov)

[17]Acute effects of tea constituents L-theanine, caffeine, and epigallocatechin gallate on cognitive function and mood: a systematic review and meta-analysis - PubMed (nih.gov)

[18]Theanine and Caffeine Content of Infusions Prepared from Commercial Tea Samples - PMC (nih.gov)

[19]The combined effects of L-theanine and caffeine on cognitive performance and mood - PubMed (nih.gov)

[20]Acute neurocognitive effects of epigallocatechin gallate (EGCG) - PubMed (nih.gov)

[21]The neuropharmacology of L-theanine(N-ethyl-L-glutamine): a possible neuroprotective and cognitive enhancing agent - PubMed (nih.gov)

[22]Natural mood foods: The actions of polyphenols against psychiatric and cognitive disorders - PMC (nih.gov)

[23]A combination of green tea extract and l-theanine improves memory and attention in subjects with mild cognitive impairment: a double-blind placebo-controlled study - PubMed (nih.gov)

[24]Mechanisms of Protection of the Brain from Ischemic Injury by Components of Tea | SpringerLink

[25]Protective effect of the green tea component, L-theanine on environmental toxins-induced neuronal cell death - PubMed (nih.gov)

[26]L-theanine promotes nitric oxide production in endothelial cells through eNOS phosphorylation - PubMed (nih.gov)

[27]How much theanine in a cup of tea? Effects of tea type and method of preparation - ScienceDirect

[28]Clinical trial on the effect of regular tea drinking on iron accumulation in genetic haemochromatosis | Gut (bmj.com)

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